Foldit Players Do It Again!

Circle with Foldit GraphicFresh off the Nature press: “Determining crystal structures through crowdsourcing and coursework”. As the paper abstract notes, “Introduction of a new feature into the computer game Foldit allows players to build and real-space refine structures into electron density maps. To assess the usefulness of this feature, we held a crystallographic model-building competition between trained crystallographers, undergraduate students, Foldit players and automatic model-building algorithms. After removal of disordered residues, a team of Foldit players achieved the most accurate structure.”

Good job, Foldit community! Read more about it here.



Happy (observed) birthday, Foldit!

Circle with Foldit GraphicFlashback with us to eight years ago and to a time when a little protein folding game with a big dream was unleashed upon the world. Since then, Foldit has been the subject of dozens of articles, numerous papers and presentations, won awards, and had our early days chronicled in a book. We have also appeared in a nearly countless number of articles and mentioned in other books!

These days, our community is focused on breaking new ground, with great tools like the Ramachandran map and an experimental client with tools for small molecule drug discovery!

With frequent and regular science chats, a steady stream of videos produced by the community, and new puzzles appearing to challenge players regularly, there’s never been a better time to get involved.

Also, we’ll be at Shoreline STEM festival this weekend if you want to say hi!



Center for Game Science on the Go!

Sylvan Grove Columns on a sunny winter day. Photo by Katherine B. Turner/ UW

We have a busy spring schedule ahead and would love to see you if you are in the area!

April 20: Bennett Elementary Family Science Night, Bellevue, WA
Our Foldit team will be out and about to share the fun of protein folding for students and parents.

April 22-23: Engineering Discovery Days, University of Washington, Seattle, WA
Come meet members from the entire team, pick up a packet of Algebra Challenge event stickers for you and your class, and try out fantastic Center for Game science titles during this annual two day event.

April 26: Spiritridge Elementary Family Science Night, Bellevue, WA
As part of our “Spring into Science” tour this year, we’re also headed to Spiritridge Elementary for our very first Family Science Night there.

May 14: Shoreline STEM Festival and Science Fair, Shoreline, WA
When we were invited to this great event last year, we had such a great time meeting everyone that we’re doing it again! This K-12 student science fair features hands-on STEM fun, robotics demonstrations, and more.

 



Foldit vs. University of Michigan Science Challenge

Circle with Foldit GraphicEarlier today we released a special puzzle challenge for the Foldit community based on a structure of a protein solved by crystallographers in the Bardwell Lab at the University of Michigan.

Recently, our scientists learned the Bardwell scientists decided to challenge a class of undergraduate biochemistry students to build a model into this unrefined density map before publishing the results. Knowing our community would also enjoy a challenge, the lab also invited Foldit players to participate!

The Foldit community has four weeks to develop a protein model that fits this density. Can Foldit players outperform the University of Michigan students—or even the crystallographers themselves?



CGS and Allen Institute Bringing Collaborative Brainpower to Neuroscience

brain Today, we’re pleased to announce our newest project in collaboration with the Allen Institute for Brain Science. With support from the National Science Foundation (NSF), we are pleased to announce plans to work with a growing community of citizen neuroscientists to develop a game whose ultimate goal is to produce a “periodic table of the neurons.” The effort will use crowd-sourcing to accelerate the discovery of 3-dimentional neuronal structures, while getting students and other non-“expert” citizens who participate excited about discovering some of the mysteries of the human brain. Read the full press release to learn more about the other creative new efforts announced by the White House yesterday to get more students and adults excited about science and space.

Our new project will join our well-established crowdsourcing efforts such as Foldit and Nanocrafter, and we couldn’t be more thrilled to continue our efforts to lend our expertise in the growing realm of citizen science.

Additionally, our Foldit community has some news regarding a special puzzle challenge via the Bardwell Lab at the University of Michigan.